Lisfranc Injury - Foot & Ankle (2024)

Updated: Feb 19 2024

Ben Sharareh MD Ventura Orthopedics
Joshua Blomberg MD Thedacare Regional Medical Center-Neenah

Lisfranc Injury

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  • Summary

    • A Lisfranc injury is a tarsometatarsal fracture dislocation characterized by traumatic disruption between the articulation of the medial cuneiform and base of the second metatarsal.

    • Diagnosis is confirmed by radiographs which may show widening of the interval between the 1st and 2nd ray.

    • Treatment is generally operative with either ORIF or arthrodesis.

  • Epidemiology

    • Incidence

      • account for 0.2% of all fractures

    • Demographics

      • males > females

      • more common in the third decade

  • ETIOLOGY

    • Pathophysiology

      • mechanism of injury

        • MVAs, falls from height, and athletic injuries

        • injury cascade

          • mechanism is usually caused by indirect rotational forces and axial load through hyper-plantarflexed forefoot

            • hyperflexion/compression/abduction moment exerted on forefoot and transmitted to the TMT articulation

            • metatarsals displaced in dorsal/lateral direction

      • pathoanatomy

        • unifying factor is disruption of the TMT joint complex

          • injuries can range from mild sprains to severe dislocations

        • may take form of purely ligamentous injuries or fracture-dislocations

          • ligamentous vs. bony injury pattern has treatment implications

    • Associated conditions

      • tarsal fractures

      • proximal metatarsal fractures

        • Lisfranc equivalent injuries can present in the form of contiguous proximal metatarsal fractures or tarsal fractures

        • can involve multiple TMT joints

  • Anatomy

    • Osteology

      • Lisfranc joint complex consists of three articulations including

        • tarsometatarsal articulation

        • intermetatarsal articulation

        • intertarsal or intercuneiform articulations

      • columns of the midfoot

        • medial column

          • includes first tarsometatarsal joint

        • middle column

          • includes second and third tarsometatarsal joints

        • lateral column

          • includes fourth and fifth tarsometatarsal joints (most mobile)

    • Ligaments

      • Lisfranc ligament

        • an interosseous ligament that goes from medial cuneiform to base of 2nd metatarsal on plantar surface

        • critical to stabilizing the 1st and 2nd tarsometatarsal joints and maintenance of the midfoot arch

        • Lisfranc ligament tightens with pronation and abduction of forefoot

      • dorsal tarsometatarsal ligaments

        • dorsal ligaments are weaker and therefore bony displacement with injury is often dorsal

      • intermetatarsal ligaments

        • between second-fifth metatarsal bases

        • no direct ligamentous attachment between first and second metatarsal

    • Biomechanics

      • Lisfranc joint complex is inherently stable with little motion due to

        • stable osseous architecture

          • second metatarsal fits in mortise created by medial cuneiform and recessed middle cuneiform, "keystone configuration"

        • ligamentous restraints

          • see individual ligaments above

  • Classification

      • Hardcastle & Myerson Classification

      • Type A

      • Complete hom*olateral dislocation

      • Type B1

      • Partial injury, medial column dislocation

      • Type B2

      • Partial injury, lateral column dislocation

      • Type C1

      • Partial injury, divergent dislocation

      • Type C2

      • Complete injury, divergent dislocation

  • Presentation

    • History

      • history of high energy trauma or sporting accident

    • Symptoms

      • severe midfoot pain

      • inability to bear weight

    • Physical exam

      • inspection & palpation

        • medial plantar ecchymosis

        • swelling throughout midfoot

        • tenderness over tarsometatarsal joint

      • motion

        • instability test

          • grasp metatarsal heads and apply dorsal force to forefoot while other hand palpates the TMT joints

            • dorsal subluxation suggests instability

            • if first and second metatarsals can be displaced medially and laterally, global instability is present and surgery is required

          • when plantar ligaments are intact, dorsal subluxation does not occur with stress exam and injury may be treated nonoperatively

      • provocative tests

        • may reproduce pain with pronation and abduction of forefoot

  • Imaging

    • Radiographs

      • recommended views

        • AP

        • lateral

        • oblique

        • weight-bearing with comparison view

          • may be necessary to confirm diagnosis

      • findings

        • five critical radiographic signs that indicate presence of midfoot instability

          • discontinuity of a line drawn from the medial base of the 2nd metatarsal to the medial side of the middle cuneiform

            • seen on AP view

            • diagnostic of Lisfranc injury

          • widening of the interval between the 1st and 2nd ray

            • seen on AP view

            • may see bony fragment (fleck sign) in 1st intermetatarsal space

              • represents avulsion of Lisfranc ligament from base of 2nd metatarsal

              • diagnostic of Lisfranc injury

          • dorsal displacement of the proximal base of the 1st or 2nd metatarsal

            • seen on lateral view

          • medial side of the base of the 4th metatarsal does not line up with medial side of cuboid

            • seen on oblique view

          • disruption of the medial column line (line tangential to the medial aspect of the navicular and the medial cuneiform)

            • seen on oblique view

    • CT

      • indications

        • useful for preoperative planning in the setting of comminuted bony injuries

        • can help identify subtle injuries

    • MRI

      • indications

        • can be used to confirm presence of purely ligamentous injury

  • Differential

    • Key Differential

      • metatarsal base fracture

      • metatarsal stress fracture

      • tarsal fracture

  • Treatment

    • Nonoperative

      • cast immobilization for 8 weeks

        • indications

          • certain non-displaced injuries that are stable with weight bearing

          • nonoperative candidates

            • nonambulatory patients

            • presence of serious vascular disease

            • severe peripheral neuropathy

        • outcomes

          • significantly lower functional and radiographic outcomes noted with non-operative management of displaced or transverse unstable injuries

    • Operative

      • temporary percutaneous pinning and delayed ORIF or arthrodesis

        • indications

          • displaced Lisfranc fracture dislocation injury with significant soft tissue swelling

        • outcomes

          • temporizing reduction and pinning and delayed definitive management with ORIF/arthrodesis has been shown to have decreased risk of wound infection in some low level studies.

      • open reduction and rigid internal fixation

        • indications

          • any evidence of instability (> 2mm shift)

          • favored in bony fracture dislocations as opposed to purely ligamentous injuries

        • outcomes

          • anatomic reduction required for a good result

          • excluding hardware removal, no difference in complications or functional outcomes between ORIF and arthrodesis

      • primary arthrodesis of the first, second and third tarsometatarsal joints

        • indications (controversial)

          • purely ligamentous arch injuries

          • delayed treatment

          • chronic deformity

          • complete Lisfranc fracture dislocations (Type A or C2)

        • outcomes

          • function outcomes

            • level 1 evidence demonstrates equivalent functional outcomes compared to primary ORIF

            • medial column tarsometatarsal fusion shown to be superior to combined medial and lateral column tarsometatarsal arthrodesis

            • some studies have shown that primary arthrodesis for complete Lisfranc fracture dislocations (Type A or C2) results in improved functional outcomes and quality of reduction compared to ORIF

          • complications

            • excluding hardware removal, no difference in complications between ORIF and arthrodesis

      • midfoot arthrodesis

        • indications

          • destabilization of the midfoot's architecture with progressive arch collapse and forefoot abduction

          • chronic Lisfranc injuries that have led to advanced midfoot arthrosis and have failed conservative therapy

  • Technique

    • Cast immobilization

      • close followup with repeat radiographs should be performed to ensure no displacement with weightbearing with non-operative management

    • Temporary percutaneous pinning

      • technique

        • reduce medial and lateral columns and stabilize with k-wires

        • K-wires left in place until soft tissue swelling subsides

        • can proceed with K-wire removal and ORIF/arthrodesis when soft tissues allow

      • timing to definitive surgery

        • can delay up to 2-3 weeks for soft tissue swelling to improve

    • Open reduction and rigid internal fixation

      • timing

        • within 24 hours or delay operative treatment until soft tissue swelling subsides (up to 2-3 weeks)

      • approach

        • single or dual longitudinal incisions can be used based on injury pattern and surgeon preference

        • longitudinal incision made in the web space between first and second rays

        • first TMT joint is exposed between the long and short hallux-extensor tendons

      • reduction & fixation

        • reduce intercuneiform instability first

        • fix first through third TMT joints with transarticular screws

          • screw fixation is more stable than K-wire fixation

          • can also span TMT joints with plates if MT base comminution is present

      • postoperative care

        • early midfoot ROM, protected weight bearing, and hardware removal (k-wires in 6-8 weeks, screws in 3-6 months)

        • gradually advance to full weight bearing at 8-10 weeks

        • if patient is asymptomatic and screws transfix only first through third TMT joints, they may be left in place

        • preclude return to vigorous athletic activities for 9 to 12 months

    • Primary arthrodesis of the first, second and third tarsometatarsal joints

      • arthrodesis & fixation

        • expose TMT joints and denude all joint surfaces of cartilage

        • use cortical screws or square plate to fuse joints

        • in the presence of both medial and lateral column dislocation, temporary lateral column pinning is recommended over lateral column arthrodesis

      • postoperative care

        • apply cast or splint for 6 weeks

        • progress weight bearing between 6 and 12 weeks in removable boot

        • full weight bearing in standard shoes by 12 weeks post-op

    • Midfoot arthrodesis

      • arthrodesis & fixation

        • expose TMT joints and midfoot and remove cartilage from first, second, and third TMT joints

        • add bone graft

        • reduce the deformity using windlass mechanism

        • variety of definitive fixation constructs exist

      • postoperative care

        • apply cast or splint for 6 weeks

        • progress weight bearing between 6 and 12 weeks in removable boot

        • begin weight bearing as tolerated at 12 weeks if evidence of healing is noted on radiographs

  • Complications

    • Posttraumatic arthritis

      • incidence

        • most common complication

      • risk factors

        • delayed treatment

        • ORIF

          • up to 80% risk with non-anatomic ORIF

            • 54% of patients have symptomatic OA at ~10 years followed ORIF

      • treatment

        • treat advanced midfoot arthrosis with midfoot arthrodesis

    • Malunion

      • risk factors

        • non-anatomic ORIF of Lisfranc injury

      • treatment

        • shoe modifications (cushioned heel with rocker sole)

          • indications

            • nonsurgical candidate

        • malunion correction with primary arthrodesis

          • indications

            • surgical candidate that has failed non-operative treatment

    • Nonunion

      • risk factors

        • smoking

      • treatment

        • revision arthrodesis with bone grafting

          • indicated unless patient is elderly and low demand

    • Hardware removal

      • incidence

        • ~75% of patients who undergo ORIF

          • often a planned secondary procedure, required to allow the TMT joints to return to motion

        • ~20% of patients following arthrodesis

    • Deep infection

      • incidence

        • 3-4%

      • risk factors

        • significant soft tissue swelling at time of definitive surgery

      • treatment

        • irrigation and debridement, possible hardware removal.

    • Planovalgus foot deformity

      • risk factors

        • non-operative management

        • non-anatomic reduction following ORIF

  • Prognosis

    • Overall Impact on Life Quality

      • significant variability regarding return to full activity given heterogenous group of patients in nearly all studies

        • in the military population, at ~3 year follow-up, ~70% patients undergoing ORIF or primary arthrodesis were able to resume occupationally required daily running.

    • Poor prognostic variables

      • missed diagnosis

        • easily missed and diagnosis is critical

        • missed injuries can result in progressive foot planovalgus deformity

          • result in chronic pain and ambulatory dysfunction

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